Identification of an in Vivo Inhibitor of Bacillus Anthracis Sterne Spore Germination
نویسندگان
چکیده
*Correspondence should be addressed to Ernesto Abel-Santos or Jürgen Brojatsch. EAS: Department of Chemistry, University of Nevada Las Vegas, 4505 Maryland Pkwy-Box 454003, Las Vegas, NV 89154, Tel. 702 895-2608, Fax. 702 895-4072, E-mail: [email protected]. JB: Department of Microbiology and Immunology, Albert Einstein College of Medicine, Golding 404, 1300 Morris Park Avenue, Bronx, NY 10461, Tel. 718 430-3079, Fax. 718 430-8711, E-mail: [email protected].
منابع مشابه
Identification of an in vivo inhibitor of Bacillus anthracis spore germination.
Germination of Bacillus anthracis spores into the vegetative form is an essential step in anthrax pathogenicity. This process can be triggered in vitro by the common germinants inosine and alanine. Kinetic analysis of B. anthracis spore germination revealed synergy and a sequential mechanism between inosine and alanine binding to their cognate receptors. Because inosine is a critical germinant ...
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